A DNA tetrahedron-based molecular beacon for tumor-related mRNA detection in living cells.
نویسندگان
چکیده
Due to its low cytotoxicity, high resistance to enzymatic degradation, and cellular permeability, a DNA tetrahedron-based molecular beacon (DTMB) is designed for tumor-related TK1 mRNA detection in living cells, where the target sequence can induce the tetrahedron from contraction to extension, resulting in fluorescence restoration.
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 11 شماره
صفحات -
تاریخ انتشار 2016